INDONESIAN HALAL HARD CAPSULE

  • Fredy Fredy Kurniawan1 Chemistry Department, Faculty of Science and Data Analytics, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia.
  • Ita Ulfin Chemistry Department, Faculty of Science and Data Analytics, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia.
  • Hendro Juwono Chemistry Department, Faculty of Science and Data Analytics, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia.
Keywords: Porang, glucomannan, extract, capsule, Indonesia

Abstract

Halal hard capsule have been made from Indonesian local plant, i.e. porang, Amorphophallus oncophyllus. The main component from porang, i.e. glucomannan, was extracted by maceration method using ethanol. A 4% of glucomannan was dissolved in demineralized water under heating condition to form a gel. Furthermore, the gel was molded to form a hard capsule. For improving the hard-capsule quality, the addition of papaya leaves and pineapple fruit extracts were investigated. The effect of temperature and time of hard capsule formation were also observed. The best condition obtained at 40°C for 30 minutes. The appearance of porang hard capsules with and without papaya leaves and pineapple fruit extracts were similar with commercial hard capsule. The solubility of porang hard capsule in water and acid solution are around 15 and 5 minutes, respectively. The result also has no significant difference from commercial hard capsules that available in the market. 

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References

Abdullah Amqizal, H.I., Al-Kahtani, H.A., Ismail, E.A., Hayat, K., Jaswir, I., 2017. Identification and verification of porcine DNA in commercial gelatin and gelatin containing processed foods. Food Control 78, 297–303. https://doi.org/10.1016/j.foodcont.2017.02.024

Ahmad, A.N., Abdul Rahman, R., Othman, M., Ungku Zainal Abidin, U.F., 2017. Critical success factors affecting the implementation of halal food management systems: Perspective of halal executives, consultants and auditors. Food Control 74, 70–78. https://doi.org/10.1016/j.foodcont.2016.11.031

Berardi, A., Bisharat, L., Cespi, M., Basheti, I.A., Bonacucina, G., Pavoni, L., AlKhatib, H.S., 2017. Controlled release properties of zein powder filled into hard gelatin capsules. Powder Technol. 320, 703–713. https://doi.org/10.1016/j.powtec.2017.07.093

Chen, X., Wang, S., Lu, M., Chen, Y., Zhao, L., Li, W., Yuan, Q., Norde, W., Li, Y., 2014. Formation and Characterization of Light-Responsive TEMPO-Oxidized Konjac Glucomannan Microspheres. Biomacromolecules 15, 2166–2171. https://doi.org/10.1021/bm500327m

Chen, Y., Zhao, H., Liu, X., Li, Z., Liu, B., Wu, J., Shi, M., Norde, W., Li, Y., 2016. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. Carbohydr. Polym. 143, 262–269. https://doi.org/10.1016/j.carbpol.2016.01.072

Duconseille, A., Astruc, T., Quintana, N., Meersman, F., Sante-Lhoutellier, V., 2015. Gelatin structure and composition linked to hard capsule dissolution: A review. Food Hydrocoll. 43, 360–376. https://doi.org/10.1016/j.foodhyd.2014.06.006

Firdausi, S., Kurniawan, F., 2016. Corrosion Inhibition by Tithonia diversifolia (Hemsl) A. Gray leaves extract for 304 SS in hydrochloric acid solution. J. Phys. Conf. Ser. 710, 012042. https://doi.org/10.1088/1742-6596/710/1/012042

Gullapalli, R.P., Mazzitelli, C.L., 2017. Gelatin and Non-Gelatin Capsule Dosage Forms. J. Pharm. Sci. 106, 1453–1465. https://doi.org/10.1016/j.xphs.2017.02.006

Hoag, S.W., 2017. Chapter 27 - Capsules Dosage Form: Formulation and Manufacturing Considerations, in: Qiu, Y., Chen, Y., Zhang, G.G.Z., Yu, L., Mantri, R.V. (Eds.), Developing Solid Oral Dosage Forms (Second Edition). Academic Press, Boston, pp. 723–747. https://doi.org/10.1016/B978-0-12-802447-8.00027-3

Indis, N.A., Kurniawan, F., 2016. Determination of free radical scavenging activity from aqueous extract of Curcuma mangga by DPPH method. J. Phys. Conf. Ser. 710, 012043. https://doi.org/10.1088/1742-6596/710/1/012043

Jian, W., Siu, K.-C., Wu, J.-Y., 2015. Effects of pH and temperature on colloidal properties and molecular characteristics of Konjac glucomannan. Carbohydr. Polym. 134, 285–292. https://doi.org/10.1016/j.carbpol.2015.07.050

Kurniawan, F., Madurani, K.A., Wahyulis, N.C., 2017. Preliminary Study of Water Repellent Properties of Red Pepper Seed Oil. IOP Conf. Ser. Mater. Sci. Eng. 180, 012278. https://doi.org/10.1088/1757-899X/180/1/012278

Kurniawan, F., Sulistiyana, Ulfin, I., 2014. New Bacterial Cellulose Membranes from Chayote Fruit and Bamboo Shoots. Int. J. Appl. Chem. 10, 101–112.

Li, X., Jiang, F., Ni, X., Yan, W., Fang, Y., Corke, H., Xiao, M., 2015. Preparation and characterization of konjac glucomannan and ethyl cellulose blend films. Food Hydrocoll. 44, 229–236. https://doi.org/10.1016/j.foodhyd.2014.09.027

Rabadiya, B., 2013. A Review : Capsule shell material from gelatin to non animal origin material. Int. J. Pharm. Res. Biosci. 2.

Rana, V., Rai, P., Tiwary, A.K., Singh, R.S., Kennedy, J.F., Knill, C.J., 2011. Modified gums: Approaches and applications in drug delivery. Carbohydr. Polym. 83, 1031–1047. https://doi.org/10.1016/j.carbpol.2010.09.010

Riaz, M.N., Chaudry, M.M., 2003. Halal Food Production. CRC Press.

Sherry Ku, M., Li, W., Dulin, W., Donahue, F., Cade, D., Benameur, H., Hutchison, K., 2010. Performance qualification of a new hypromellose capsule: Part I. Comparative evaluation of physical, mechanical and processability quality attributes of Vcaps Plus®, Quali-V® and gelatin capsules. Int. J. Pharm. 386, 30–41. https://doi.org/10.1016/j.ijpharm.2009.10.050

Tieman, M., Ghazali, M.C., 2014. Halal Control Activities and Assurance Activities in Halal Food Logistics. Procedia - Soc. Behav. Sci., International Halal Conference InHAC 2012 121, 44–57. https://doi.org/10.1016/j.sbspro.2014.01.1107

Xiao, M., Dai, S., Wang, L., Ni, X., Yan, W., Fang, Y., Corke, H., Jiang, F., 2015. Carboxymethyl modification of konjac glucomannan affects water binding properties. Carbohydr. Polym. 130, 1–8. https://doi.org/10.1016/j.carbpol.2015.05.001

Xu, X., Li, B., Kennedy, J.F., Xie, B.J., Huang, M., 2007. Characterization of konjac glucomannan–gellan gum blend films and their suitability for release of nisin incorporated therein. Carbohydr. Polym. 70, 192–197. https://doi.org/10.1016/j.carbpol.2007.03.017

Zhang, H., Yoshimura, M., Nishinari, K., Williams, M. a. K., Foster, T.J., Norton, I.T., 2001. Gelation behaviour of konjac glucomannan with different molecular weights. Biopolymers 59, 38–50. https://doi.org/10.1002/1097-0282(200107)59:1<38::AID-BIP1004>3.0.CO;2-A

Zhou, B., Liu, J., Ye, T., Wang, Y., Xu, W., Li, B., 2014. Phase separation in mixtures of ovalbumin and konjac glucomannan: Physicochemical and microscopic investigations. Int. J. Biol. Macromol. 70, 167–173. https://doi.org/10.1016/j.ijbiomac.2014.06.030

Published
2020-01-30
How to Cite
Fredy Kurniawan1F., Ulfin, I., & Juwono, H. (2020). INDONESIAN HALAL HARD CAPSULE. PROSIDING SEMINAR NASIONAL DMI, 1, 59-67. Retrieved from https://www.dmi-journals.org/prosiding/article/view/11